Understanding how slow brain rhythms affect sleep quality
CRCNS: Mechanisms and consequences of infraslow oscillations in sleep
This study is looking at how certain slow brain waves during sleep help us move between different sleep stages, especially from deep sleep to dreaming, and it hopes to find ways to improve sleep quality and health for people with sleep disorders.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pennsylvania NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-11192346 on NIH RePORTER |
What this research studies
This research investigates the role of infraslow oscillations in sleep, focusing on how these rhythms influence the transition between different sleep states, particularly from non-REM to REM sleep. By using a combination of experimental studies and biophysical computational modeling, the research aims to uncover the mechanisms that generate these rhythms and their effects on sleep architecture. Patients may benefit from insights into how these rhythms affect sleep quality and overall health, potentially leading to improved treatments for sleep disorders.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals experiencing sleep disturbances or disorders, particularly those with affective disorders.
Not a fit: Patients without sleep issues or those not affected by chronic conditions related to sleep may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and treatment options for sleep disorders, enhancing sleep quality for patients.
How similar studies have performed: Other research has shown promising results in understanding brain rhythms and their impact on sleep, suggesting that this approach could yield valuable insights.
Where this research is happening
Philadelphia, United States
- University of Pennsylvania — Philadelphia, United States (Active)
Researchers
- Principal investigator: Weber, Franz L — University of Pennsylvania
- Study coordinator: Weber, Franz L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.