Understanding how slits3 signaling affects fat tissue that generates heat
Mechanisms of slits3 signaling in thermogenic adipose tissue
This study is looking at how a specific signaling process in brown fat helps your body stay warm and burn energy, with the hope of finding new ways to help people manage weight and improve their overall health.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11066529 on NIH RePORTER |
What this research studies
This research investigates the role of slits3 signaling in brown adipose tissue (BAT), which is crucial for regulating body temperature and energy expenditure. By analyzing how BAT functions and adapts to cold environments, the study aims to uncover mechanisms that could enhance the body's ability to burn fat and improve metabolic health. The approach includes advanced techniques like single-cell transcriptomic analysis to explore the specific cellular responses within BAT. This research could lead to new strategies for combating obesity and related metabolic diseases.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults who are struggling with obesity or metabolic conditions and are interested in innovative treatment approaches.
Not a fit: Patients who do not have issues related to obesity or metabolic disorders may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide new therapeutic strategies for obesity and metabolic disorders by enhancing the body's ability to burn fat.
How similar studies have performed: Previous research has shown promising results in understanding the mechanisms of brown adipose tissue, indicating that this approach has potential for significant advancements.
Where this research is happening
New York, United States
- New York University — New York, United States (Active)
Researchers
- Principal investigator: Shamsi, Farnaz — New York University
- Study coordinator: Shamsi, Farnaz
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.