NIH-funded research R01 grant

Understanding how sleep problems in children can be treated effectively

Official title: A mechanistic understanding of treatment-related outcomes of sleep disordered breathing using functional near infrared spectroscopy

Funded at University of Maryland Baltimore · NIH-11037889 · Data updated 2026-11-12

This study is looking at how surgery to remove tonsils and adenoids can help children with sleep problems that affect their behavior and school performance, and it aims to find out which kids will benefit the most from the surgery.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Maryland Baltimore
NIH-funded
Lab location1 site (Baltimore, United States)
Project startFebruary 1, 2023
Project endJanuary 31, 2028
Funding year2025
Award (this year)$533,892
NIH project number5R01HL167012-03
Project IDNIH-11037889 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are children aged 0-15 years who exhibit symptoms of sleep disordered breathing.

Less likely to help

Patients who do not have sleep disordered breathing or those whose symptoms are not significant enough to warrant treatment may not benefit from this research.

What this research studies

This research investigates sleep disordered breathing (SDB) in children, which can lead to behavioral issues and poor academic performance. The study aims to understand how surgical treatment, specifically adenotonsillectomy, affects outcomes for children with SDB. By using advanced imaging techniques, the research will explore the brain's response to treatment and develop a predictive model to identify which children are most likely to benefit from surgery versus those who may do well with observation. This approach seeks to enhance treatment decisions and improve overall quality of life for affected children.

Why it matters

Potential benefit: If successful, this research could lead to better treatment strategies for children with sleep disordered breathing, improving their behavior and academic performance.

How similar studies have gone: Previous research has shown that understanding the mechanisms of sleep disorders can lead to improved treatment outcomes, suggesting this approach has potential for success.

Where this research is happening

  • University of Maryland Baltimore
    Baltimore, United States
    Active

Researchers

  • Principal investigator: Isaiah, Amal — University of Maryland Baltimore
  • Study coordinator: Isaiah, Amal

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.