Understanding how sleep patterns affect adolescent brain function

Phenotyping and Biobanking Core

['FUNDING_OTHER'] · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · NIH-10892089

This study is looking at how staying up late, not getting enough sleep, and having a messed-up sleep schedule affect the brain in teenagers aged 13 to 15, to see how these sleep habits relate to thinking skills, sensitivity to rewards, and the risk of using substances.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF PITTSBURGH AT PITTSBURGH (nih funded)
Locations1 site (PITTSBURGH, UNITED STATES)
Trial IDNIH-10892089 on ClinicalTrials.gov

What this research studies

This research focuses on how late sleep timing, short sleep duration, and circadian misalignment impact brain function in adolescents aged 13 to 15 years. By recruiting participants with specific sleep characteristics, the study aims to explore the relationship between sleep patterns and cognitive control, reward sensitivity, and substance use risk. The research also includes a biobanking component, collecting biological specimens to support future studies on molecular rhythms. This comprehensive approach combines human and animal studies to better understand adolescent development.

Who could benefit from this research

Good fit: Ideal candidates for participation are adolescents aged 13 to 15 years who experience varied sleep patterns.

Not a fit: Patients outside the age range of 13 to 15 years or those without sleep-related issues may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved strategies for managing sleep-related issues in adolescents, potentially reducing risks associated with cognitive impairment and substance use.

How similar studies have performed: Previous research has shown promising results in understanding the impact of sleep on cognitive functions in adolescents, indicating that this approach has potential for success.

Where this research is happening

PITTSBURGH, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.