Understanding how sleep loss and circadian disruption affect health
Biomarkers and Altered Metabolic Pathways during Sleep Loss and Circadian Disruption
['FUNDING_CAREER'] · UNIVERSITY OF UTAH · NIH-10668411
This study is looking at how not getting enough sleep and having messed-up sleep schedules can affect your health, and it aims to find specific signs in your body that can help doctors understand and treat issues like inflammation, depression, anxiety, and diabetes better for people who struggle with sleep problems.
Quick facts
| Phase | ['FUNDING_CAREER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF UTAH (nih funded) |
| Locations | 1 site (SALT LAKE CITY, UNITED STATES) |
| Trial ID | NIH-10668411 on ClinicalTrials.gov |
What this research studies
This research investigates the impact of sleep loss and circadian disruption on health by identifying specific biomarkers associated with these conditions. It aims to understand how insufficient sleep and misaligned circadian rhythms contribute to various health issues, including inflammation, depression, anxiety, and diabetes. The study will analyze metabolic pathways and biochemical mechanisms to develop tools for better diagnosis and personalized treatment options for affected individuals. By focusing on these biomarkers, the research seeks to improve overall health outcomes for those suffering from sleep-related disorders.
Who could benefit from this research
Good fit: Ideal candidates for this research include adults over 21 years old who experience sleep disorders or work irregular hours that disrupt their circadian rhythms.
Not a fit: Patients who do not experience sleep or circadian rhythm issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnosis and treatment options for individuals suffering from sleep and circadian disorders.
How similar studies have performed: Previous research has shown promise in identifying biomarkers related to sleep health, suggesting that this approach could yield valuable insights.
Where this research is happening
SALT LAKE CITY, UNITED STATES
- UNIVERSITY OF UTAH — SALT LAKE CITY, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: DEPNER, CHRISTOPHER MICHAEL — UNIVERSITY OF UTAH
- Study coordinator: DEPNER, CHRISTOPHER MICHAEL
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.