Understanding how sleep is controlled in tiny worms
Mechanisms of Sleep Regulation in C. elegans
['FUNDING_OTHER'] · UNIVERSITY OF WISCONSIN-MADISON · NIH-10910105
This study is looking at how tiny worms sleep when they're stressed, hoping to learn more about the basic ways sleep works, which could help us understand sleep in people too.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF WISCONSIN-MADISON (nih funded) |
| Locations | 1 site (MADISON, UNITED STATES) |
| Trial ID | NIH-10910105 on ClinicalTrials.gov |
What this research studies
This research investigates the mechanisms that regulate sleep using the model organism C. elegans, a type of tiny worm. By focusing on how cellular stress activates specific signaling pathways in a single neuron to induce sleep, the study aims to uncover fundamental genetic and neural processes involved in sleep regulation. The approach involves observing behavioral changes in these worms under stress conditions to gain insights that may be applicable to understanding sleep in more complex organisms, including humans.
Who could benefit from this research
Good fit: Ideal candidates for benefiting from this research include individuals suffering from sleep disorders or related neurological conditions.
Not a fit: Patients who do not have sleep-related issues or neurological disorders may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to new insights into sleep disorders and potential treatments for improving sleep quality in humans.
How similar studies have performed: Previous studies using simple model organisms have shown success in uncovering basic mechanisms of sleep regulation, suggesting that this approach is promising.
Where this research is happening
MADISON, UNITED STATES
- UNIVERSITY OF WISCONSIN-MADISON — MADISON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: WANG, HAN — UNIVERSITY OF WISCONSIN-MADISON
- Study coordinator: WANG, HAN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.