Understanding how sleep helps us remember sequences of information

CRCNS: Neural computations underlying sequence memory consolidation in sleep

NIH-funded research University of California, San Diego · NIH-10861922

This study is looking at how sleep helps our brains remember things better, especially how we store and recall related information, using experiments with mice to learn more about the brain's memory processes that could also apply to people.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California, San Diego NIH-funded
Lab location1 site (La Jolla, United States)
Project IDNIH-10861922 on NIH RePORTER

What this research studies

This research investigates the role of sleep in consolidating memory, particularly focusing on how our brains store and retrieve sequences of related information. By using computational models and experiments with mice, the study aims to uncover the mechanisms in the hippocampus and neocortex that facilitate memory consolidation during slow-wave sleep. The researchers will analyze brain activity patterns to understand how sequences are learned and reinforced while we sleep, potentially leading to insights about memory processes in humans.

Who could benefit from this research

Good fit: Ideal candidates for benefiting from this research include individuals experiencing memory-related issues or those interested in enhancing their learning capabilities.

Not a fit: Patients with severe neurological disorders that impair sleep or memory may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could enhance our understanding of memory consolidation, potentially leading to improved strategies for learning and memory retention in patients.

How similar studies have performed: Previous research has shown promising results in understanding memory consolidation during sleep, making this approach a continuation of established findings.

Where this research is happening

La Jolla, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.