Understanding how sleep apnea affects health outcomes
Phenotyping Mechanistic Pathways for Adverse Health Outcomes in Sleep Apnea
This study is looking at how obstructive sleep apnea affects your health and aims to find better ways to help you feel better with CPAP therapy by understanding your specific sleep patterns and heart responses, so you can get the most benefit from your treatment.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Brigham and Women's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10914102 on NIH RePORTER |
What this research studies
This research investigates the adverse health effects of obstructive sleep apnea (OSA) and aims to improve treatment outcomes with continuous positive airway pressure (CPAP) therapy. By characterizing OSA more precisely through new metrics that assess hypoxemia, heart rate responses, and sleep fragmentation, the study seeks to identify patients who are at higher risk for negative health outcomes. Participants will undergo assessments to determine their physiological responses to OSA, and those with significant burdens may benefit more from CPAP therapy. The goal is to enhance the effectiveness of treatment and improve overall health for individuals with OSA.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with obstructive sleep apnea who are experiencing adverse health outcomes.
Not a fit: Patients without a diagnosis of obstructive sleep apnea or those who do not experience significant health issues related to the condition may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more personalized and effective treatments for patients with sleep apnea, reducing their risk of serious health complications.
How similar studies have performed: Previous research has shown that more precise characterization of sleep apnea can lead to better treatment outcomes, suggesting that this approach may yield significant advancements.
Where this research is happening
Boston, United States
- Brigham and Women's Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Azarbarzin, Ali — Brigham and Women's Hospital
- Study coordinator: Azarbarzin, Ali
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.