NIH-funded research Fellowship grant

Understanding how sleep and circadian rhythms affect thinking in older adults at risk of dementia

Official title: Examining Sleep, Circadian Rhythms, and Cognitive Functioning in Older Adults at Risk of Dementia

Funded at Boston University (Charles River Campus) · NIH-10911786 · Data updated 2026-11-12

This study is looking at how sleep habits and body clocks affect thinking skills in older adults who might be at risk for dementia, especially those noticing changes in their memory or thinking, to find early signs of cognitive issues and ways to help improve brain health.

More Dementia research and trials

Quick facts

Grant typeFellowship grant
Study typeNIH-funded research
Funding institutionBoston University (Charles River Campus)
NIH-funded
Lab location1 site (Boston, United States)
Project startJuly 1, 2023
Project endJune 30, 2027
Funding year2024
Award (this year)$38,352
NIH project number5F31AG081066-02
Project IDNIH-10911786 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are older adults aged 65 and above who are experiencing subjective cognitive decline.

Less likely to help

Patients who are not experiencing any cognitive decline or are under 65 years old may not benefit from this research.

What this research studies

This research investigates the relationship between sleep patterns, circadian rhythms, and cognitive functioning in older adults who may be at risk for dementia. It focuses on how disturbances in sleep and circadian rhythms can impact cognitive abilities, particularly in those experiencing subjective cognitive decline (SCD). By examining these factors, the research aims to identify early signs of cognitive impairment and potential interventions that could help improve cognitive health. The study will also explore how stress may influence these relationships, providing a comprehensive view of the factors affecting cognitive decline.

Why it matters

Potential benefit: If successful, this research could lead to earlier diagnosis and targeted interventions for cognitive decline in older adults.

How similar studies have gone: Previous research has shown promising results in understanding the links between sleep disturbances and cognitive decline, suggesting that this approach could yield valuable insights.

Where this research is happening

  • Boston University (Charles River Campus)
    Boston, United States
    Active

Researchers

  • Principal investigator: Mcdowell, Celina F — Boston University (Charles River Campus)
  • Study coordinator: Mcdowell, Celina F

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.