Understanding how sleep and circadian rhythms affect substance use in adolescents

Center for Adolescent Reward, Rhythms and Sleep (CARRS)

['FUNDING_OTHER'] · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · NIH-10892086

This study is looking at how sleep habits and body clocks affect the brain's reward system and the chances of substance use in teenagers, with the hope of finding new ways to help prevent substance abuse among young people.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF PITTSBURGH AT PITTSBURGH (nih funded)
Locations1 site (PITTSBURGH, UNITED STATES)
Trial IDNIH-10892086 on ClinicalTrials.gov

What this research studies

This research investigates the relationship between sleep patterns, circadian rhythms, and substance use in adolescents. By integrating studies in both humans and rodents, the project aims to explore how changes in sleep and circadian alignment influence the brain's reward system and the risk of substance use. The research employs experimental manipulations to assess these effects, with the goal of developing new prevention and intervention strategies for substance abuse among young people. The findings could provide insights into how biological and environmental factors contribute to substance use risk during adolescence.

Who could benefit from this research

Good fit: Ideal candidates for this research include adolescents and young adults who may be experiencing sleep disturbances or are at risk for substance use.

Not a fit: Patients who are not adolescents or young adults, or those without sleep or substance use issues, may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to effective strategies for preventing substance abuse in adolescents by addressing sleep and circadian rhythm issues.

How similar studies have performed: Previous research has shown promising results in understanding the links between sleep patterns and substance use, suggesting that this approach could yield valuable insights.

Where this research is happening

PITTSBURGH, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.