Understanding how sleep and body clock affect metabolic health
Official title: Uncovering sleep and circadian mechanisms contributing to adverse metabolic health
Funded at Oregon Health & Science University · NIH-10898074 · Data updated 2026-11-12
This study is looking at how your sleep habits and body clock affect your health, especially if you're dealing with obesity or diabetes, and it invites you to join a 14-day program where you'll follow specific sleep and eating schedules to help us learn more about how these factors influence your metabolism.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Oregon Health & Science University NIH-funded |
| Lab location | 1 site (Portland, United States) |
| Project start | August 15, 2023 |
| Project end | July 31, 2027 |
| Funding year | 2024 |
| Award (this year) | $573,368 |
| NIH project number | 5R01HL169317-02 |
| Project ID | NIH-10898074 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals experiencing obesity or diabetes who may also have irregular sleep patterns.
✕Less likely to help
Patients with stable metabolic health and regular sleep patterns may not benefit from this research.
What this research studies
This research investigates the relationship between sleep patterns, circadian rhythms, and metabolic health, particularly focusing on obesity and diabetes. It aims to identify how chronic sleep restriction and circadian disruption impact energy intake, food choices, and glucose tolerance. By conducting a 14-day randomized control trial, the study will analyze these factors to better understand their combined effects on metabolism. Patients may be asked to participate in controlled sleep and eating schedules to gather data on their metabolic responses.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for managing obesity and diabetes through better sleep and circadian health.
How similar studies have gone: Previous research has shown promising results in understanding the links between sleep, circadian rhythms, and metabolic health, suggesting that this approach could yield valuable insights.
Where this research is happening
-
Oregon Health & Science University
Portland, United States Active
Researchers
- Principal investigator: Mchill, Andrew William — Oregon Health & Science University
- Study coordinator: Mchill, Andrew William
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.