Understanding how sleep affects treatment outcomes for opioid-use disorder
Official title: Value of Sleep Metrics in Predicting Opioid-Use Disorder Treatment Outcomes: Leadership and Data Coordinating Center
Funded at Harvard Pilgrim Health Care, INC. · NIH-10931556 · Data updated 2026-11-12
This study is looking at how sleep problems might affect the success of treatments for people dealing with opioid-use disorder, and it aims to find ways to improve recovery by focusing on better sleep.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Harvard Pilgrim Health Care, INC. NIH-funded |
| Lab location | 1 site (Canton, UNITED STATES) |
| Project start | September 30, 2023 |
| Project end | August 31, 2027 |
| Funding year | 2024 |
| Award (this year) | $616,083 |
| NIH project number | 5U01DA059472-02 |
| Project ID | NIH-10931556 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with opioid-use disorder who are undergoing treatment.
✕Less likely to help
Patients who do not have opioid-use disorder or those not engaged in treatment may not benefit from this research.
What this research studies
This research investigates the relationship between sleep metrics and the effectiveness of treatments for opioid-use disorder (OUD). By analyzing how sleep disturbances impact retention in care, the study aims to identify specific sleep and circadian rhythm measures that could predict treatment outcomes. A team of experts in sleep science and addiction medicine will collaborate to gather and analyze data from multiple sites, focusing on improving patient care and treatment adherence. The findings could lead to new interventions targeting sleep issues to enhance recovery from OUD.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment outcomes for patients with opioid-use disorder by addressing sleep-related issues.
How similar studies have gone: Previous research has indicated that sleep disturbances can significantly affect treatment outcomes in various conditions, suggesting that this approach may yield valuable insights.
Where this research is happening
-
Harvard Pilgrim Health Care, INC.
Canton, United States Active
Researchers
- Principal investigator: Wang, Rui — Harvard Pilgrim Health Care, INC.
- Study coordinator: Wang, Rui
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.