Understanding how sleep affects thinking in people with new-onset temporal lobe epilepsy
Official title: Characterizing Sleep Signatures and its effects on Cognition in New-Onset Temporal Lobe Epilepsy
Funded at University of California at Davis · NIH-10836551 · Data updated 2026-11-12
This study is looking at how sleep affects memory and attention in people who have just been diagnosed with temporal lobe epilepsy, hoping to find ways to help improve both their sleep and thinking skills.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California at Davis NIH-funded |
| Lab location | 1 site (Davis, United States) |
| Project start | July 1, 2023 |
| Project end | June 30, 2028 |
| Funding year | 2024 |
| Award (this year) | $192,564 |
| NIH project number | 5K23NS131574-02 |
| Project ID | NIH-10836551 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals aged 21 and older who have recently been diagnosed with temporal lobe epilepsy.
✕Less likely to help
Patients with epilepsy types other than temporal lobe epilepsy or those without cognitive or sleep issues may not benefit from this research.
What this research studies
This research investigates the relationship between sleep patterns and cognitive function in individuals diagnosed with new-onset temporal lobe epilepsy (TLE). The study aims to identify abnormal sleep architecture and its impact on memory and attention, which are often impaired in TLE patients. By using observational methods and advanced monitoring techniques, the research seeks to uncover the underlying mechanisms that contribute to cognitive deficits in this population. The findings could lead to improved treatment strategies that address both sleep and cognitive issues in TLE.
Why it matters
Potential benefit: If successful, this research could lead to better management of sleep and cognitive problems in patients with temporal lobe epilepsy, ultimately improving their quality of life.
How similar studies have gone: Previous research has indicated that addressing sleep issues can significantly improve cognitive outcomes in epilepsy patients, suggesting a promising avenue for this study.
Where this research is happening
-
University of California at Davis
Davis, United States Active
Researchers
- Principal investigator: Oyegbile-Chidi, Temitayo — University of California at Davis
- Study coordinator: Oyegbile-Chidi, Temitayo
Related research
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This study is looking at how late-onset epilepsy in people aged 60 and older might be linked to memory and thinking problems, like those seen in Alzheimer's disease, to see if it could help us find ways to spot and address these issues early on.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.