Understanding how sleep affects opioid use disorder
The Collaboration Linking Opioid Use Disorder and Sleep ("CLOUDS") Study
['FUNDING_U01'] · YALE UNIVERSITY · NIH-11166828
This study is looking at how not getting enough sleep might affect people with opioid use disorder who are getting treatment, and it aims to find new ways to help improve their sleep and support their recovery.
Quick facts
| Phase | ['FUNDING_U01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | YALE UNIVERSITY (nih funded) |
| Locations | 1 site (NEW HAVEN, UNITED STATES) |
| Trial ID | NIH-11166828 on ClinicalTrials.gov |
What this research studies
This research investigates the relationship between sleep deficiency and opioid use disorder (OUD) in patients undergoing medication-assisted treatment (MAT). By conducting an observational cohort study with 220 patients, the study will assess various aspects of sleep and circadian rhythms using advanced techniques like polysomnography and wrist actigraphy. The goal is to uncover potential causal mechanisms that link poor sleep to ongoing opioid use and treatment retention issues, ultimately aiming to identify new therapeutic strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with opioid use disorder who are currently stabilized on medication-assisted treatment.
Not a fit: Patients who are not currently receiving medication-assisted treatment for opioid use disorder may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies for individuals with opioid use disorder by addressing sleep-related issues.
How similar studies have performed: Previous research has indicated that addressing sleep issues can improve treatment outcomes in substance use disorders, suggesting that this approach may yield valuable insights.
Where this research is happening
NEW HAVEN, UNITED STATES
- YALE UNIVERSITY — NEW HAVEN, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: YAGGI, HENRY KLAR — YALE UNIVERSITY
- Study coordinator: YAGGI, HENRY KLAR
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.