Understanding how sleep affects cravings and emotions in people treated for opioid use disorder.
Official title: Investigating mechanisms underpinning outcomes in people on opioid agonist treatment for OUD: Disentangling sleep and circadian rhythm influences on craving and emotion regulation
Funded at Emma Pendleton Bradley Hospital · NIH-10932897 · Data updated 2026-11-12
This study is looking at how your sleep quality and body clock affect cravings and emotions while you're being treated for opioid use disorder, with the hope of finding ways to improve your recovery by focusing on better sleep.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emma Pendleton Bradley Hospital NIH-funded |
| Lab location | 1 site (Riverside, UNITED STATES) |
| Project start | September 30, 2023 |
| Project end | August 31, 2027 |
| Funding year | 2024 |
| Award (this year) | $1,038,035 |
| NIH project number | 5R01DA059469-02 |
| Project ID | NIH-10932897 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals currently receiving medication-assisted treatment for opioid use disorder who experience sleep disturbances.
✕Less likely to help
Patients who are not undergoing treatment for opioid use disorder or do not have sleep-related issues may not benefit from this research.
What this research studies
This research investigates how sleep quality and circadian rhythms influence cravings and emotional regulation in individuals undergoing treatment for opioid use disorder (OUD). By examining the relationship between medication-assisted treatment and sleep disturbances, the study aims to identify specific sleep-related factors that could improve treatment outcomes. The approach includes assessing sleep patterns and cognitive measures to better understand how these elements interact with opioid treatment. The ultimate goal is to develop targeted interventions that can enhance recovery for patients on opioid medications.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies that enhance recovery outcomes for individuals with opioid use disorder.
How similar studies have gone: Previous research has shown that addressing sleep issues can significantly improve treatment outcomes in various substance use disorders, suggesting a promising avenue for this study.
Where this research is happening
-
Emma Pendleton Bradley Hospital
Riverside, United States Active
Researchers
- Principal investigator: Carskadon, Mary a — Emma Pendleton Bradley Hospital
- Study coordinator: Carskadon, Mary a
Related research
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.