Understanding how sleep affects cravings and emotions in people treated for opioid use disorder.

Investigating mechanisms underpinning outcomes in people on opioid agonist treatment for OUD: Disentangling sleep and circadian rhythm influences on craving and emotion regulation

NIH-funded research Emma Pendleton Bradley Hospital · NIH-10932897

This study is looking at how your sleep quality and body clock affect cravings and emotions while you're being treated for opioid use disorder, with the hope of finding ways to improve your recovery by focusing on better sleep.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionEmma Pendleton Bradley Hospital NIH-funded
Lab location1 site (Riverside, UNITED STATES)
Project IDNIH-10932897 on NIH RePORTER

What this research studies

This research investigates how sleep quality and circadian rhythms influence cravings and emotional regulation in individuals undergoing treatment for opioid use disorder (OUD). By examining the relationship between medication-assisted treatment and sleep disturbances, the study aims to identify specific sleep-related factors that could improve treatment outcomes. The approach includes assessing sleep patterns and cognitive measures to better understand how these elements interact with opioid treatment. The ultimate goal is to develop targeted interventions that can enhance recovery for patients on opioid medications.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals currently receiving medication-assisted treatment for opioid use disorder who experience sleep disturbances.

Not a fit: Patients who are not undergoing treatment for opioid use disorder or do not have sleep-related issues may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved treatment strategies that enhance recovery outcomes for individuals with opioid use disorder.

How similar studies have performed: Previous research has shown that addressing sleep issues can significantly improve treatment outcomes in various substance use disorders, suggesting a promising avenue for this study.

Where this research is happening

Riverside, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.