Understanding how sleep affects caregivers of people with Alzheimer's disease

Social and Biological Influences of Sleep in ADRD Spousal Caregivers

NIH-funded research Rice University · NIH-11160261

This study is looking at how feeling lonely and isolated affects the health of people who care for loved ones with Alzheimer's and similar conditions, especially focusing on their sleep and overall well-being, and it involves 300 caregivers who will share their experiences and undergo some health checks over two weeks.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionRice University NIH-funded
Lab location1 site (Houston, United States)
Project IDNIH-11160261 on NIH RePORTER

What this research studies

This research investigates the impact of social isolation and loneliness on the health of spousal caregivers for individuals with Alzheimer's disease and related dementias. It aims to identify how these factors contribute to caregiver burden and physical health outcomes, particularly focusing on sleep quality. The study will involve 300 caregivers who will complete various assessments related to their mental and physical well-being, including blood tests to evaluate inflammation and cellular aging. Additionally, caregivers will undergo momentary assessments of their emotional state and heart rate variability over a two-week period to better understand the relationship between sleep and caregiving stress.

Who could benefit from this research

Good fit: Ideal candidates for this research are spousal caregivers of individuals with Alzheimer's disease or related dementias, particularly those experiencing social isolation or loneliness.

Not a fit: Patients who are not caregivers or those who do not have a spouse with Alzheimer's disease or related dementias may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved health and well-being for caregivers by identifying effective interventions to enhance their sleep quality.

How similar studies have performed: Previous research has indicated that addressing social and biological factors can significantly improve caregiver health outcomes, suggesting that this approach may yield beneficial results.

Where this research is happening

Houston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Alzheimer's disease and related dementiaAlzheimer's disease and related disordersAlzheimer's disease or a related dementiaAlzheimer's disease or a related disorder
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.