Understanding how sleep affects brain function and memory.
CRCNS: Acetylcholine and state-dependent neural network reorganization
['FUNDING_R01'] · UNIVERSITY OF MICHIGAN AT ANN ARBOR · NIH-11080363
This study looks at how different types of sleep affect our memory and brain function, and it aims to help people understand how better sleep can improve thinking and feelings.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF MICHIGAN AT ANN ARBOR (nih funded) |
| Locations | 1 site (ANN ARBOR, UNITED STATES) |
| Trial ID | NIH-11080363 on ClinicalTrials.gov |
What this research studies
This research investigates the critical role of sleep in brain function, particularly focusing on how different sleep states—wake, non-rapid eye movement (NREM), and rapid eye movement (REM)—influence memory consolidation. By examining the dynamics of brain networks during these states, the study aims to uncover how acetylcholine signaling and other mechanisms contribute to the reorganization of brain circuits essential for memory storage. Patients may benefit from insights into how improving sleep could enhance cognitive function and emotional well-being.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals experiencing sleep disorders or cognitive impairments, particularly those related to autism spectrum disorders.
Not a fit: Patients without sleep disturbances or cognitive impairments may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for cognitive and emotional disorders linked to sleep disturbances.
How similar studies have performed: Previous research has shown promising results in understanding the relationship between sleep and cognitive function, suggesting that this approach could yield valuable insights.
Where this research is happening
ANN ARBOR, UNITED STATES
- UNIVERSITY OF MICHIGAN AT ANN ARBOR — ANN ARBOR, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ZOCHOWSKI, MICHAL R — UNIVERSITY OF MICHIGAN AT ANN ARBOR
- Study coordinator: ZOCHOWSKI, MICHAL R
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: autism spectral disorder, autism spectrum disorder