Understanding how sleep affects blood flow in the brain
Project 3: Dissecting the neural and neuromodulatory control mechanisms of arterial dynamics during sleep
['FUNDING_OTHER'] · UNIVERSITY OF ROCHESTER · NIH-10898613
This study is looking at how sleep affects blood flow in the brain and how brain signals influence this process, using mice to help us understand how sleep helps keep our brains healthy.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF ROCHESTER (nih funded) |
| Locations | 1 site (ROCHESTER, UNITED STATES) |
| Trial ID | NIH-10898613 on ClinicalTrials.gov |
What this research studies
This research investigates the changes in blood vessel dynamics during sleep and how these changes are influenced by neural activity and chemical signals in the brain. By using advanced imaging techniques, researchers will observe the behavior of blood vessels in sleeping mice and manipulate neural activity to see how it affects blood flow. The study aims to uncover the mechanisms that drive the pumping of cerebrospinal fluid, which is crucial for brain health. This could lead to insights into how sleep contributes to brain function and maintenance.
Who could benefit from this research
Good fit: Ideal candidates for this research would be individuals experiencing sleep disorders or those interested in the effects of sleep on brain health.
Not a fit: Patients with acute neurological conditions or those not experiencing sleep-related issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of sleep's role in brain health and potentially lead to new treatments for sleep-related disorders.
How similar studies have performed: Previous research has shown promising results in understanding the relationship between sleep and brain function, making this approach both relevant and potentially impactful.
Where this research is happening
ROCHESTER, UNITED STATES
- UNIVERSITY OF ROCHESTER — ROCHESTER, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: DREW, PATRICK JAMES — UNIVERSITY OF ROCHESTER
- Study coordinator: DREW, PATRICK JAMES
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.