Understanding How Skin Repairs Itself
Live Imaging of Skin Regeneration
This research helps us understand how skin cells renew and repair themselves, which is important for conditions like cancer and degenerative diseases.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project ID | NIH-11167704 on NIH RePORTER |
What this research studies
Our bodies constantly renew and repair tissues using special cells called stem cells. When this process goes wrong, it can lead to serious health issues like cancer or degenerative diseases. This project uses advanced imaging techniques to watch skin cells in live animals, allowing us to see how these stem cells make decisions about growth and repair in real time. We want to uncover the detailed molecular steps that guide these cells to ensure healthy skin and prevent disease. By understanding these fundamental processes, we hope to find new ways to support tissue health.
Who could benefit from this research
Good fit: This foundational research does not directly involve patient participation at this stage, but future clinical applications could benefit individuals with skin cancers or other skin-related degenerative conditions.
Not a fit: Patients seeking immediate new treatments or direct clinical intervention will not find direct benefit from this basic science project.
Why it matters
Potential benefit: If successful, this work could lead to new insights into how to prevent or treat diseases like skin cancer and other degenerative conditions by better controlling cell regeneration.
How similar studies have performed: The research builds upon the group's prior success in tracking epithelial cells in live animals, but the current focus on visualizing molecular events at the tissue level is a novel adaptation.
Where this research is happening
New Haven, United States
- Yale University — New Haven, United States (Active)
Researchers
- Principal investigator: Greco, Valentina — Yale University
- Study coordinator: Greco, Valentina
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.