Understanding how skin injuries from chemical exposure cause inflammation
Official title: Integrated spatial omics to elucidate conserved inflammatory mechanisms of vesicant-induced skin injury
Funded at University of Texas Med Br Galveston · NIH-10953395 · Data updated 2026-11-12
This study is looking at how skin injuries from chemical burns cause inflammation, and it's for anyone who has experienced this type of injury; the researchers want to find better ways to treat the inflammation and help people heal faster.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Texas Med Br Galveston NIH-funded |
| Lab location | 1 site (Galveston, United States) |
| Project start | September 17, 2024 |
| Project end | August 31, 2027 |
| Funding year | 2024 |
| Award (this year) | $317,240 |
| NIH project number | 1R34AR084669-01 |
| Project ID | NIH-10953395 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals who have experienced chemical exposure resulting in skin injuries, particularly those with vesicant-induced damage.
✕Less likely to help
Patients with skin injuries not caused by chemical exposure or those who do not exhibit inflammatory responses may not benefit from this research.
What this research studies
This research investigates the inflammatory mechanisms that occur in skin injuries caused by chemical exposure, specifically focusing on vesicants. By using advanced spatial omics techniques, the study aims to capture both the local tissue response and the underlying biological processes involved in inflammation. This approach allows researchers to better understand how inflammation develops over time and how it can be effectively treated with existing anti-inflammatory therapies. The goal is to develop new strategies to mitigate the damage caused by chemical burns and improve patient outcomes.
Why it matters
Potential benefit: If successful, this research could lead to the development of effective treatments for patients suffering from chemical burns and related skin injuries.
How similar studies have gone: Previous research has shown promise in targeting inflammatory pathways for treating burn injuries, suggesting that this approach may lead to significant advancements.
Where this research is happening
-
University of Texas Med Br Galveston
Galveston, United States Active
Researchers
- Principal investigator: Prideaux, Brendan — University of Texas Med Br Galveston
- Study coordinator: Prideaux, Brendan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.