Understanding how skin functions differently in males and females

Defining Sexual Dimorphism in the Skin

NIH-funded research Harvard Medical School · NIH-10993820

This study is looking at how skin works differently in men and women by checking out how hair follicle stem cells act under the influence of hormones, especially before and after puberty, to help us understand skin health and issues better for everyone.

Quick facts

Grant typeFellowship grant
Study typeNIH-funded research
Funding institutionHarvard Medical School NIH-funded
Lab location1 site (Boston, United States)
Project IDNIH-10993820 on NIH RePORTER

What this research studies

This research investigates the differences in skin function between biological sexes, focusing on how stem cells in hair follicles behave differently in males and females. The study will explore how sex hormones influence these behaviors during various life stages, particularly before and after puberty. By examining the proliferation patterns of hair follicle stem cells, the research aims to uncover the underlying mechanisms of sexual dimorphism in skin. This could lead to a better understanding of skin health and disease in different sexes.

Who could benefit from this research

Good fit: Ideal candidates for participation or benefit from this research include individuals aged 21 and older who are interested in understanding skin health and its relation to biological sex.

Not a fit: Patients who are under 21 years old or those with skin conditions unrelated to hormonal influences may not receive benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved treatments for skin-related conditions that differ by sex.

How similar studies have performed: Previous research has shown promising results in understanding sexual dimorphism in other tissues, suggesting that this approach may yield valuable insights.

Where this research is happening

Boston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.