Understanding how skin cells grow and become specialized
Regulators of epidermal growth and differentiation
This research looks at how skin cells grow and change at a fundamental level, which could help us understand conditions like eczema.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Diego NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project ID | NIH-11126871 on NIH RePORTER |
What this research studies
Our skin constantly renews itself, and this project explores the tiny genetic switches that control how skin cells grow and mature. We are focusing on specific factors that help turn genes on or off, guiding skin stem cells to either multiply or become specialized skin cells. Understanding these processes is key to maintaining healthy skin and could offer new insights into skin conditions. This work aims to uncover the fundamental ways our skin keeps itself healthy and repairs itself.
Who could benefit from this research
Good fit: This foundational research is relevant to adults experiencing skin conditions like atopic dermatitis, though direct patient participation is not currently described.
Not a fit: Patients whose conditions are unrelated to skin cell growth and differentiation may not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this work could lead to new ways to treat skin conditions where growth and differentiation are disrupted, such as eczema.
How similar studies have performed: The researchers have already identified specific factors that play a role in skin cell growth and differentiation, building on previous findings.
Where this research is happening
La Jolla, United States
- University of California, San Diego — La Jolla, United States (Active)
Researchers
- Principal investigator: Sen, George L — University of California, San Diego
- Study coordinator: Sen, George L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.