Understanding how skin cells affect melanoma growth
In vivo characterization of keratinocytes in the melanoma microenvironment
This study is looking at how skin cells and melanoma cells interact using zebrafish to help us understand how melanoma might change skin cells in ways that could help the cancer grow, with the hope of finding better ways to manage melanoma and improve treatment for patients.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Weill Medical Coll of Cornell Univ NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10872297 on NIH RePORTER |
What this research studies
This research investigates the interactions between keratinocytes, a type of skin cell, and melanoma cells using zebrafish as a model. The study aims to understand how melanoma can induce changes in keratinocytes that may promote tumor growth. By observing these interactions in real-time, researchers will assess the role of specific proteins and transcription factors involved in this process. The findings could provide insights into how to better control melanoma progression and improve patient outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals at risk for melanoma or those with early-stage melanoma.
Not a fit: Patients with advanced melanoma or those who do not have any skin-related conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing or treating melanoma by targeting the interactions between skin cells and tumor cells.
How similar studies have performed: Other research has shown promising results in understanding tumor microenvironments, suggesting that this approach could yield valuable insights.
Where this research is happening
New York, United States
- Weill Medical Coll of Cornell Univ — New York, United States (Active)
Researchers
- Principal investigator: Ma, Yilun — Weill Medical Coll of Cornell Univ
- Study coordinator: Ma, Yilun
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.