Understanding how skin can heal without scars

Neuroimmune Control of Scarless Skin Regeneration

['FUNDING_R01'] · UNIVERSITY OF PENNSYLVANIA · NIH-11098713

This study looks at how certain animals can heal their skin without scars and aims to find new ways to help people heal better after injuries, so they can avoid scars and improve skin repair.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF PENNSYLVANIA (nih funded)
Locations1 site (PHILADELPHIA, UNITED STATES)
Trial IDNIH-11098713 on ClinicalTrials.gov

What this research studies

This research investigates the biological processes involved in skin healing, focusing on how some vertebrates can regenerate skin without forming scars. It explores the role of specific receptors and immune cells in promoting skin regeneration after injuries. By studying models of skin healing, the research aims to uncover new therapeutic approaches that could enhance the body's natural ability to heal wounds without scarring. Patients may benefit from insights that could lead to better treatments for scar prevention and skin repair.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals with skin injuries or conditions that result in scarring.

Not a fit: Patients with non-skin related injuries or conditions may not receive benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new therapies that enable scarless skin healing, improving both physical and emotional outcomes for patients.

How similar studies have performed: Previous research has shown promise in understanding skin regeneration mechanisms, indicating potential for success in this area.

Where this research is happening

PHILADELPHIA, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.