Understanding how signals shape embryonic development and prevent birth defects
Spatiotemporal Regulation of Developmental Pattern Formation
This study looks at how tiny sea urchin larvae grow and develop their skeletons by exploring the signals that guide their development, with the hope that understanding these processes can help prevent birth defects in humans.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston University (Charles River Campus) NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-11001488 on NIH RePORTER |
What this research studies
This research investigates the complex processes that guide embryonic development and the formation of body structures, particularly focusing on how different signals interact over time and space. Using sea urchin larvae as a model, the study aims to create a detailed model of how these signals influence the development of the skeleton. By employing advanced computational modeling and systems biology approaches, the research seeks to uncover the molecular mechanisms behind these processes, which could lead to better understanding and prevention of birth defects.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with a family history of congenital abnormalities or those interested in developmental biology.
Not a fit: Patients with fully developed congenital conditions that do not involve ongoing developmental processes may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for preventing birth defects and enhancing developmental health.
How similar studies have performed: Other research has shown promise in understanding developmental processes through similar modeling approaches, indicating potential for success in this area.
Where this research is happening
Boston, United States
- Boston University (Charles River Campus) — Boston, United States (Active)
Researchers
- Principal investigator: Bradham, Cynthia a — Boston University (Charles River Campus)
- Study coordinator: Bradham, Cynthia a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.