Understanding how signals from deeper brain areas affect thinking and behavior

Identify the schemata by which subcortical signals influence frontal cortical dynamics and cognitive behaviors

NIH-funded research Allen Institute · NIH-11009598

This study looks at how certain parts of the brain work together to affect thinking and movement, which could help us understand and treat cognitive disorders better.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionAllen Institute NIH-funded
Lab location1 site (Seattle, United States)
Project IDNIH-11009598 on NIH RePORTER

What this research studies

This research investigates how signals from subcortical brain regions influence the dynamics of the frontal cortex, which is crucial for cognitive functions and behaviors. By examining the interactions between these brain areas, the study aims to uncover how different inputs from the basal ganglia and thalamus affect processes like memory and movement. Patients may benefit from insights into how cognitive disorders arise and how they can be treated. The research employs advanced modeling techniques to predict neural activity patterns that can be tested through neurophysiological methods.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals with cognitive disorders or those experiencing difficulties with memory and movement.

Not a fit: Patients with purely sensory disorders or those not experiencing cognitive or movement-related issues may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and treatment options for cognitive disorders.

How similar studies have performed: Previous research has shown promising results in understanding brain dynamics and their impact on behavior, indicating that this approach has potential for success.

Where this research is happening

Seattle, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.