Understanding how sex differences affect psychosis in children and adolescents

Sex-Specific Psychosis Biotypes: Informed Data-driven Neurobiological and Genomic Markers for Early Risk Detection

NIH-funded research Georgia State University · NIH-11050594

This study is looking at how psychosis shows up differently in boys and girls to help find it earlier and create better treatments, focusing on young people aged 0-20.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionGeorgia State University NIH-funded
Lab location1 site (Atlanta, United States)
Project IDNIH-11050594 on NIH RePORTER

What this research studies

This research investigates the differences in how psychosis manifests in boys and girls, focusing on early detection and tailored interventions. By analyzing brain connectivity and genetic markers in a large group of individuals aged 0-20, the study aims to identify distinct subgroups of psychosis that vary by sex. The approach combines advanced data analysis techniques to uncover biological differences that could lead to better treatment strategies. Ultimately, the goal is to improve outcomes for young people at risk of developing psychotic disorders.

Who could benefit from this research

Good fit: Ideal candidates for this research include children and adolescents aged 0-20 who may be at risk for developing psychotic disorders.

Not a fit: Patients who are older than 20 or those who do not exhibit any risk factors for psychotic disorders may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective early detection and personalized treatment options for young individuals at risk of psychosis.

How similar studies have performed: Previous research has shown promise in identifying sex-specific differences in mental health conditions, suggesting that this approach could yield valuable insights.

Where this research is happening

Atlanta, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.