Understanding how sex differences affect Alzheimer's disease risk
Decoding the impact of sex differences on Alzheimer's disease risk
['FUNDING_R01'] · BAYLOR COLLEGE OF MEDICINE · NIH-10889109
This study is looking at how genes linked to Alzheimer's disease might affect men and women differently, with the goal of finding better ways to screen for and prevent the disease for everyone.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | BAYLOR COLLEGE OF MEDICINE (nih funded) |
| Locations | 1 site (HOUSTON, UNITED STATES) |
| Trial ID | NIH-10889109 on ClinicalTrials.gov |
What this research studies
This research investigates how genetic factors related to Alzheimer's disease (AD) may differ between men and women. By analyzing genetic variants and their impact on AD risk, the study aims to develop more effective screening and prevention strategies tailored to each sex. The approach combines computational methods with experimental studies to identify key genes associated with AD. This research seeks to enhance our understanding of the disease's molecular basis and improve patient outcomes through sex-specific insights.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals at risk for Alzheimer's disease, particularly those with a family history or genetic predisposition, with a focus on both men and women.
Not a fit: Patients who do not have a genetic risk for Alzheimer's disease or those with advanced stages of the disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more personalized prevention and treatment strategies for Alzheimer's disease based on sex differences.
How similar studies have performed: Previous research has shown that sex differences can significantly impact disease risk and progression, suggesting that this approach may yield valuable insights.
Where this research is happening
HOUSTON, UNITED STATES
- BAYLOR COLLEGE OF MEDICINE — HOUSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LICHTARGE, OLIVIER — BAYLOR COLLEGE OF MEDICINE
- Study coordinator: LICHTARGE, OLIVIER
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Alzheimer disease dementia, Alzheimer syndrome, Alzheimer's Disease