Understanding how sex differences affect Alzheimer's disease
Decoding the impact of sex differences on Alzheimer's disease risk
This research explores how genetic differences between men and women might influence who gets Alzheimer's disease and how it progresses.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Baylor College of Medicine NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-11115778 on NIH RePORTER |
What this research studies
Alzheimer's disease affects men and women differently, but we don't fully understand why. This project looks at the genetic makeup of individuals to find specific genetic variations that might contribute to Alzheimer's risk in men versus women. By using advanced computer methods and laboratory tests, we hope to uncover these hidden genetic links. The goal is to develop more precise ways to identify and help people based on their sex and genetic profile.
Who could benefit from this research
Good fit: This foundational genetic research is relevant for anyone concerned about Alzheimer's disease, especially those with a family history or an interest in genetic factors.
Not a fit: Patients seeking immediate new treatments or direct clinical intervention will not find direct benefit from this basic science research.
Why it matters
Potential benefit: If successful, this work could lead to personalized prevention and treatment strategies for Alzheimer's disease, tailored specifically for men and women.
How similar studies have performed: Previous large-scale genetic studies have identified many genes linked to Alzheimer's, but this project introduces a novel computational approach to specifically address sex differences.
Where this research is happening
Houston, United States
- Baylor College of Medicine — Houston, United States (Active)
Researchers
- Principal investigator: Lichtarge, Olivier — Baylor College of Medicine
- Study coordinator: Lichtarge, Olivier
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.