Understanding how sex and gender affect diseases
Elucidating the phenome-wide impact of sex and gender on disease
['FUNDING_R01'] · VANDERBILT UNIVERSITY MEDICAL CENTER · NIH-10894879
This study is looking at how being male or female, along with other personal experiences, affects different health conditions by using a lot of health records and genetic information, all to help us better understand diseases and improve care for everyone.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | VANDERBILT UNIVERSITY MEDICAL CENTER (nih funded) |
| Locations | 1 site (NASHVILLE, UNITED STATES) |
| Trial ID | NIH-10894879 on ClinicalTrials.gov |
What this research studies
This research investigates the influence of sex and gender-related factors on various diseases by analyzing a vast collection of electronic health records linked to genetic data. By utilizing large-scale biobanks, the study aims to quantify how these factors interact with heritable diseases across the medical phenome. Patients' health information, including socioeconomic factors and trauma experiences, will be examined to uncover their associations with health outcomes. This approach leverages existing medical data to enhance our understanding of disease mechanisms and improve patient care.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with heritable diseases who have diverse backgrounds in terms of sex and gender.
Not a fit: Patients who do not have heritable diseases or those whose health records do not include relevant sex and gender-related exposures may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more personalized and effective treatments based on sex and gender differences in disease manifestation.
How similar studies have performed: Previous research has shown promising results in understanding the impact of sex and gender on health outcomes, indicating that this approach has potential for significant findings.
Where this research is happening
NASHVILLE, UNITED STATES
- VANDERBILT UNIVERSITY MEDICAL CENTER — NASHVILLE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: DAVIS, LEA K — VANDERBILT UNIVERSITY MEDICAL CENTER
- Study coordinator: DAVIS, LEA K
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cardiovascular Diseases