Understanding how sex affects heart and metabolic health
Sex Differences in Cardiometabolic Health and Disease
This study looks at how being male or female affects the risk of heart and metabolic diseases, with the goal of improving how we diagnose and treat these conditions for everyone.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Los Angeles NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project ID | NIH-10919840 on NIH RePORTER |
What this research studies
This research investigates how sex differences influence the risk of cardiometabolic diseases, aiming to improve diagnosis and treatment for both men and women. It explores various factors, including the effects of estrogen, genetic variations, and differences between XX and XY chromosomes. The research utilizes preclinical mouse models, human stem cell lines, and existing human population datasets to translate findings into practical applications. By examining these factors, the research seeks to identify specific risks and develop tailored prevention strategies.
Who could benefit from this research
Good fit: Ideal candidates for participation are individuals at risk for cardiometabolic diseases, particularly those with a family history or existing conditions related to heart health.
Not a fit: Patients who do not have cardiometabolic conditions or those who are not interested in understanding sex-specific health risks may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized treatments for cardiometabolic diseases based on sex differences.
How similar studies have performed: Previous research has shown promising results in understanding sex differences in various health conditions, indicating that this approach could yield significant insights.
Where this research is happening
Los Angeles, United States
- University of California Los Angeles — Los Angeles, United States (Active)
Researchers
- Principal investigator: Reue, Karen — University of California Los Angeles
- Study coordinator: Reue, Karen
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.