Understanding how serotonin affects reward processing and impulsivity in adolescents
Serotonin modulation of the development of neural circuits underlying reward processing and impulsivity in adolescents
This study is looking at how serotonin affects the way the brain develops during the teenage years, especially in relation to things like rewards and impulsive behavior, to help understand and prevent conditions like ADHD and borderline personality disorder.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Dartmouth College NIH-funded |
| Lab location | 1 site (Hanover, United States) |
| Project ID | NIH-11012387 on NIH RePORTER |
What this research studies
This research investigates how serotonin influences the development of brain circuits related to reward processing and impulsivity during adolescence. By examining both typical and atypical development, the study aims to identify factors that lead to psychiatric disorders such as ADHD and borderline personality disorder. Utilizing a combination of human longitudinal data and mouse models, the research will explore the underlying neural mechanisms and behavioral changes that occur during this critical developmental period. The goal is to inform targeted interventions that could prevent or alter the trajectory of these disorders.
Who could benefit from this research
Good fit: Ideal candidates for this research include adolescents aged 12 to 20 who may be experiencing issues related to impulsivity or reward processing.
Not a fit: Patients outside the adolescent age range or those without impulsivity or reward processing issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for preventing and treating impulsivity and reward-related disorders in adolescents.
How similar studies have performed: Previous research has shown promise in understanding the role of serotonin in adolescent development, but this specific approach combining human and animal models is relatively novel.
Where this research is happening
Hanover, United States
- Dartmouth College — Hanover, United States (Active)
Researchers
- Principal investigator: Nautiyal, Katherine M — Dartmouth College
- Study coordinator: Nautiyal, Katherine M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.