Understanding how serine metabolism affects stem cell behavior and tissue healing
Dissecting the role of serine metabolism in stem cell fate and tissue regeneration
This study is looking at how a substance called serine affects skin stem cells, which are important for healing wounds and growing hair, to find new ways to help people heal better and manage skin issues like inflammation and cancer.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Weill Medical Coll of Cornell Univ NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11010351 on NIH RePORTER |
What this research studies
This research investigates the role of serine metabolism in the behavior of stem cells, particularly those in the skin, which are crucial for healing wounds and growing hair. By examining how these stem cells use metabolic inputs, the study aims to uncover new ways to enhance tissue regeneration and manage conditions like inflammation and skin cancers. The approach includes analyzing the effects of serine on stem cell functions and their ability to regenerate hair follicles and repair skin. This could lead to innovative treatments that improve healing processes in patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions that impair wound healing or those at risk for skin cancers.
Not a fit: Patients with non-skin-related conditions or those not affected by issues related to stem cell function may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that enhance wound healing and tissue regeneration in patients.
How similar studies have performed: Previous research has shown promising results in understanding metabolic influences on stem cell behavior, suggesting that this approach could yield significant insights.
Where this research is happening
New York, United States
- Weill Medical Coll of Cornell Univ — New York, United States (Active)
Researchers
- Principal investigator: Novak, Jesse Stephen Swyer — Weill Medical Coll of Cornell Univ
- Study coordinator: Novak, Jesse Stephen Swyer
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.