Understanding how sepsis affects recovery in children after intensive care
Official title: Pediatric Recovery After Sepsis Treatment in the Pediatric Intensive Care Unit
Funded at University of Connecticut Storrs · NIH-10899755 · Data updated 2026-11-12
This study is looking at how sepsis affects kids' bodies over time after they've been treated in the hospital, to find ways to help them recover better and live healthier lives.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Connecticut Storrs NIH-funded |
| Lab location | 1 site (Storrs-Mansfield, United States) |
| Project start | September 1, 2022 |
| Project end | August 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $249,000 |
| NIH project number | 5R00GM145411-05 |
| Project ID | NIH-10899755 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are children aged 0-11 years who have been treated for sepsis in the PICU.
✕Less likely to help
Patients who have not experienced sepsis or those outside the pediatric age range may not benefit from this research.
What this research studies
This research investigates the long-term physical effects of sepsis on children who have been treated in the Pediatric Intensive Care Unit (PICU). By analyzing existing data, the study aims to identify factors that contribute to physical dysfunction in these children after they leave the hospital. The research will focus on the role of inflammation and other biological markers in recovery, providing insights that could help improve care for pediatric patients. The ultimate goal is to enhance the quality of life for children recovering from sepsis.
Why it matters
Potential benefit: If successful, this research could lead to improved recovery strategies and interventions for children who have survived sepsis.
How similar studies have gone: Previous research has shown promising results in understanding the impacts of sepsis on recovery, but this specific approach focusing on pediatric patients is relatively novel.
Where this research is happening
-
University of Connecticut Storrs
Storrs-Mansfield, United States Active
Researchers
- Principal investigator: Perry-Eaddy, Mallory a — University of Connecticut Storrs
- Study coordinator: Perry-Eaddy, Mallory a
Related research
Other NIH-funded projects on the same topics.
-
Understanding how sepsis affects recovery in children after intensive care
This study is looking at how sepsis affects kids' physical abilities over time after they've been treated in the PICU, to help us understand their recovery better and improve care for future patients.
-
Phthalate Exposure and How It Affects Newborns in the NICU
This grant looks at how chemicals called phthalates in the NICU environment may affect the health and development of newborns, especially those born prematurely.
-
Improving care for opioid use disorder in the ICU
This project helps hospital staff in intensive care units provide better care for patients with opioid use disorder.
-
Juggling Work and Family for Parents of Very Preterm Babies
A study to understand how work and family demands affect parents of very preterm infants and how this shapes their ability to support their baby’s development.
-
Implementing SDOH screening and referrals in the NICU to support fragile newborns
A NICU-based program to screen newborns and families for social needs and connect them to services that can improve health and development.
-
Attenuating Depression with Internet CBT to Slow Cognitive Decline in Older ICU Survivors
A new online cognitive behavioral therapy program is being tested to help older ICU survivors who are experiencing depressive symptoms and may be at risk for cognitive decline.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.