Understanding how sensory sensitivity changes in autism over time
Neural mechanisms of sensory reactivity and regulation in autism across development
This study is looking at how some kids with autism feel extra sensitive to things like loud sounds or being touched, and it aims to understand how this sensitivity changes as they grow up, so we can find better ways to help them feel more comfortable.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Los Angeles NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project ID | NIH-11013314 on NIH RePORTER |
What this research studies
This research investigates sensory over-responsivity (SOR), a condition where individuals experience extreme sensitivity to stimuli like loud noises or touch, particularly in youth with autism spectrum disorders (ASD). The study aims to identify the developmental trajectory of SOR and the underlying neurobiological mechanisms that contribute to its persistence or decline. By examining brain responses and connectivity during sensory experiences, the research seeks to inform the development of effective interventions for those affected. Participants may undergo assessments involving brain imaging and sensory tasks to better understand their sensory processing.
Who could benefit from this research
Good fit: Ideal candidates for this research include children and adolescents diagnosed with autism spectrum disorder who experience sensory over-responsivity.
Not a fit: Patients without autism spectrum disorder or those who do not experience sensory sensitivities may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to targeted interventions that improve the quality of life for individuals with autism by addressing sensory sensitivities.
How similar studies have performed: Previous research has begun to uncover neural mechanisms related to sensory processing in autism, suggesting that this approach has potential for meaningful insights and interventions.
Where this research is happening
Los Angeles, United States
- University of California Los Angeles — Los Angeles, United States (Active)
Researchers
- Principal investigator: Green, Shulamite Abra — University of California Los Angeles
- Study coordinator: Green, Shulamite Abra
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.