Understanding how sensory processing affects posttraumatic stress disorder (PTSD)

A Neurosensory Account of Posttraumatic Stress Disorder

['FUNDING_R01'] · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · NIH-11184994

This study is looking at how the way our brains process sensory information might affect people with PTSD, especially how certain brain areas related to fear can make symptoms worse, and it’s designed for anyone wanting to understand more about the connection between their senses and their feelings after trauma.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON (nih funded)
Locations1 site (HOUSTON, UNITED STATES)
Trial IDNIH-11184994 on ClinicalTrials.gov

What this research studies

This research investigates the relationship between sensory processing and posttraumatic stress disorder (PTSD). It aims to understand how dysfunctions in the brain's fear circuitry, particularly involving the amygdala and prefrontal cortex, contribute to the symptoms of PTSD. The study will explore three specific mechanisms of sensory cortical disinhibition that may worsen PTSD symptoms, including responses to novelty and threats. By integrating sensory processing with emotional regulation, the research seeks to provide a more comprehensive understanding of PTSD.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with posttraumatic stress disorder (PTSD) who experience significant sensory processing difficulties.

Not a fit: Patients without a diagnosis of PTSD or those whose symptoms are not related to sensory processing may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved treatments for PTSD by addressing the sensory processing issues that contribute to the disorder.

How similar studies have performed: While the integration of sensory processing with PTSD is a relatively novel approach, previous research has shown promising results in understanding the fear circuitry involved in PTSD.

Where this research is happening

HOUSTON, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.