Understanding how sensory organs form during development
Official title: Physical, Molecular and Cellular Regulation of Sensory Organ Formation
Funded at New York University School of Medicine · NIH-11026637 · Data updated 2026-11-12
This study looks at how tiny fish embryos, called zebrafish, develop their sense organs by tracking how certain cells move and work together, which could help us understand and improve treatments for people with sensory organ development issues.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University School of Medicine NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | December 3, 2024 |
| Project end | November 30, 2029 |
| Funding year | 2025 |
| Award (this year) | $563,343 |
| NIH project number | 1R01NS140233-01 |
| Project ID | NIH-11026637 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research would include individuals with genetic or developmental disorders impacting sensory organ formation.
✕Less likely to help
Patients with fully developed sensory organs and no related disorders may not receive any benefit from this research.
What this research studies
This research investigates the mechanisms behind the formation of sensory organs in developing embryos, specifically using zebrafish as a model organism. It focuses on how certain cells migrate and split to create neuronal clusters, guided by chemical signals. The study employs advanced techniques to visualize and manipulate these processes, aiming to uncover the roles of specific proteins and cellular interactions in organ formation. Patients may benefit from insights gained into developmental disorders related to sensory organ formation.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and potential treatments for developmental disorders affecting sensory organs.
How similar studies have gone: Other research has shown success in using zebrafish models to study developmental processes, indicating that this approach is promising and has been validated in similar contexts.
Where this research is happening
-
New York University School of Medicine
New York, United States Active
Researchers
- Principal investigator: Knaut, Holger — New York University School of Medicine
- Study coordinator: Knaut, Holger
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.