Understanding how sensory neurons affect inflammation
Functional interrogation of sensory neurons in inflammation
['FUNDING_CAREER'] · SCRIPPS RESEARCH INSTITUTE, THE · NIH-10890865
This study is looking at how itch-sensing nerves in our body might affect chronic inflammatory diseases, with the hope of finding better treatments for people dealing with these conditions.
Quick facts
| Phase | ['FUNDING_CAREER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | SCRIPPS RESEARCH INSTITUTE, THE (nih funded) |
| Locations | 1 site (LA JOLLA, UNITED STATES) |
| Trial ID | NIH-10890865 on ClinicalTrials.gov |
What this research studies
This research investigates the role of sensory neurons, particularly those that detect itch, in the development and progression of chronic inflammatory diseases. By using advanced genetic and viral techniques, the study aims to uncover how these neurons interact with the immune system and contribute to inflammation in various conditions. The goal is to better understand the mechanisms behind these interactions, which could lead to more effective treatments for patients suffering from inflammatory disorders.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals suffering from chronic inflammatory conditions, particularly those involving skin or visceral organ inflammation.
Not a fit: Patients with acute inflammatory conditions or those not affected by sensory neuron-related inflammation may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that more effectively manage or treat chronic inflammatory diseases.
How similar studies have performed: While the specific focus on pruriceptors in inflammatory diseases is relatively novel, similar research has shown promise in understanding the role of sensory neurons in other contexts.
Where this research is happening
LA JOLLA, UNITED STATES
- SCRIPPS RESEARCH INSTITUTE, THE — LA JOLLA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: HILL, ROSE Z — SCRIPPS RESEARCH INSTITUTE, THE
- Study coordinator: HILL, ROSE Z
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.