Understanding how sensory nerve disruption affects bone mass in the tibia
The Impact of Disrupting Sensory Innervation on Tibial Bone Mass
This study is looking at how nerves in your leg affect bone health, especially in the shin bone, to see if problems with these nerves can lead to weaker bones and more fractures, which could help find better ways to prevent and treat tibial fractures for patients like you.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of New England NIH-funded |
| Lab location | 1 site (Biddeford, United States) |
| Project ID | NIH-10895590 on NIH RePORTER |
What this research studies
This research investigates the role of sensory nerves in maintaining bone health, specifically focusing on the tibia. It aims to understand how disrupting these nerves impacts bone mineral density and the risk of fractures. By studying the saphenous nerve and its communication with bone cells, the research seeks to identify factors that contribute to low bone density and increased fracture risk. Patients may benefit from insights that could lead to better prevention and treatment strategies for tibial fractures.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals at risk for osteoporosis or those with a history of tibial fractures.
Not a fit: Patients with healthy bone density and no history of fractures are unlikely to benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for preventing tibial fractures in individuals with low bone mineral density.
How similar studies have performed: Other research has shown promising results in understanding the relationship between sensory nerves and bone health, indicating that this approach has potential for significant findings.
Where this research is happening
Biddeford, United States
- University of New England — Biddeford, United States (Active)
Researchers
- Principal investigator: Becker, Kathleen a — University of New England
- Study coordinator: Becker, Kathleen a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.