Understanding how sensory disinhibition affects traumatic memories
Official title: A Multilevel Characterization of Sensory Cortical Disinhibition in Post-Traumatic Intrusions
Funded at Mclean Hospital · NIH-10946957 · Data updated 2026-11-12
This study is looking at how certain brain processes affect unwanted memories after trauma, and it's for adults who have experienced trauma and want to help researchers understand how these memories work in the brain.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mclean Hospital NIH-funded |
| Lab location | 1 site (Belmont, United States) |
| Project start | July 10, 2024 |
| Project end | June 30, 2029 |
| Funding year | 2024 |
| Award (this year) | $179,002 |
| NIH project number | 1K23MH137459-01 |
| Project ID | NIH-10946957 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults over 21 who have experienced trauma and suffer from intrusive memories.
✕Less likely to help
Patients who have not experienced trauma or do not have issues with intrusive memories may not benefit from this research.
What this research studies
This research investigates how sensory disinhibition in the brain influences intrusive memories following trauma. By using advanced imaging techniques like magnetic resonance spectroscopy, electroencephalography, and functional magnetic resonance imaging, the study aims to explore the neural mechanisms behind these vivid memories. Participants will be trauma-exposed adults who will provide real-time reports of their intrusive memories, allowing researchers to connect brain activity with the sensory experiences of these memories. The goal is to better understand the biological underpinnings of these traumatic experiences and their impact on daily life.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for individuals suffering from intrusive memories and related mental health issues.
How similar studies have gone: Other research has shown promising results in understanding the neural mechanisms of trauma-related memories, suggesting that this approach could yield valuable insights.
Where this research is happening
-
Mclean Hospital
Belmont, United States Active
Researchers
- Principal investigator: Clancy, Kevin — Mclean Hospital
- Study coordinator: Clancy, Kevin
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.