Understanding how sensory disinhibition affects traumatic memories

A Multilevel Characterization of Sensory Cortical Disinhibition in Post-Traumatic Intrusions

NIH-funded research Mclean Hospital · NIH-10946957

This study is looking at how certain brain processes affect unwanted memories after trauma, and it's for adults who have experienced trauma and want to help researchers understand how these memories work in the brain.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionMclean Hospital NIH-funded
Lab location1 site (Belmont, United States)
Project IDNIH-10946957 on NIH RePORTER

What this research studies

This research investigates how sensory disinhibition in the brain influences intrusive memories following trauma. By using advanced imaging techniques like magnetic resonance spectroscopy, electroencephalography, and functional magnetic resonance imaging, the study aims to explore the neural mechanisms behind these vivid memories. Participants will be trauma-exposed adults who will provide real-time reports of their intrusive memories, allowing researchers to connect brain activity with the sensory experiences of these memories. The goal is to better understand the biological underpinnings of these traumatic experiences and their impact on daily life.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults over 21 who have experienced trauma and suffer from intrusive memories.

Not a fit: Patients who have not experienced trauma or do not have issues with intrusive memories may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved treatments for individuals suffering from intrusive memories and related mental health issues.

How similar studies have performed: Other research has shown promising results in understanding the neural mechanisms of trauma-related memories, suggesting that this approach could yield valuable insights.

Where this research is happening

Belmont, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.