Understanding how self-criticism and self-compassion relate to suicidal thoughts in young people

Neural Mechanisms Underlying Self-Critical Rumination and Self-Reassurance and Suicidal Thoughts and Behavior in Youth

NIH-funded research Emma Pendleton Bradley Hospital · NIH-10936125

This study is looking at how young people aged 12-15 think about themselves and how that connects to feelings of sadness or thoughts about suicide, using brain scans to understand what's happening in their minds, with the hope of finding ways to help those who might be struggling.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionEmma Pendleton Bradley Hospital NIH-funded
Lab location1 site (Riverside, UNITED STATES)
Project IDNIH-10936125 on NIH RePORTER

What this research studies

This research investigates the brain and behavioral mechanisms that contribute to self-critical thoughts and self-reassurance in youth aged 12-15. Using advanced imaging techniques like functional MRI and real-time assessments, the study aims to explore how these mental processes are linked to suicidal thoughts and behaviors. By examining brain activity in specific regions associated with self-evaluation, the research seeks to uncover the neural pathways that may influence these critical issues during a vulnerable developmental stage. The findings could provide insights into effective prevention strategies for youth at risk of suicide.

Who could benefit from this research

Good fit: Ideal candidates for participation are youth aged 12-15 who experience self-critical thoughts or suicidal ideation.

Not a fit: Patients outside the age range of 12-15 or those without self-critical thoughts or suicidal behaviors may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and interventions for preventing suicidal thoughts and behaviors in adolescents.

How similar studies have performed: Previous research has shown promising results in understanding the neural mechanisms of self-evaluation and its impact on mental health, suggesting that this approach could yield valuable insights.

Where this research is happening

Riverside, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.