Understanding how self-awareness affects relapse in opioid addiction
Neurocircuitry of clinical insight predicting relapse outcomes in opioid addiction
This study is looking at how being aware of your own addiction can affect your chances of staying on track after treatment for opioid use disorder, and it’s for people who have recently completed detox and want to understand how their thoughts about their drug use might impact their recovery.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | State University New York Stony Brook NIH-funded |
| Lab location | 1 site (Stony Brook, United States) |
| Project ID | NIH-10655449 on NIH RePORTER |
What this research studies
This research investigates the role of self-awareness in predicting relapse outcomes for individuals with opioid use disorder (OUD). It focuses on how impaired insight into one's addiction can lead to poorer treatment outcomes. Using functional magnetic resonance imaging (fMRI), participants will engage in tasks that assess their perceptions of their drug use severity and treatment needs. By comparing recently detoxified individuals with OUD to healthy controls, the study aims to identify neural markers that could help predict relapse and improve treatment adherence.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have recently detoxified from opioid use and are currently undergoing medication-assisted therapy.
Not a fit: Patients who are not struggling with opioid addiction or those who are not currently in treatment may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies that enhance self-awareness in patients, potentially reducing relapse rates.
How similar studies have performed: While the study of insight in addiction is emerging, this specific approach using fMRI to investigate its neural correlates in opioid addiction is relatively novel.
Where this research is happening
Stony Brook, United States
- State University New York Stony Brook — Stony Brook, United States (Active)
Researchers
- Principal investigator: Moeller, Scott J — State University New York Stony Brook
- Study coordinator: Moeller, Scott J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.