Understanding how seasonal coronaviruses affect COVID-19 in macaques
Official title: Pan Coronavirus Genomic Surveillance of a Large NHP Colony
Funded at Tulane University of Louisiana · NIH-10739824 · Data updated 2026-11-12
This study is looking at how having immunity from common seasonal coronaviruses affects COVID-19 in rhesus macaques, helping us understand more about the viruses and how we can improve vaccines in the future.
Quick facts
| Grant type | R03 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Tulane University of Louisiana NIH-funded |
| Lab location | 1 site (New Orleans, United States) |
| Project start | November 14, 2022 |
| Project end | October 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $87,500 |
| NIH project number | 5R03AI174152-02 |
| Project ID | NIH-10739824 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research would be individuals interested in the effects of coronaviruses and their immunity, particularly those involved in veterinary or infectious disease research.
✕Less likely to help
Patients who are not involved in research related to coronaviruses or who do not have an interest in animal studies may not receive any benefit from this research.
What this research studies
This research investigates the impact of preexisting immunity to seasonal coronaviruses on COVID-19 disease in a large colony of rhesus macaques. The study will involve sampling nasal and rectal sites to quantify coronavirus infections and using advanced sequencing techniques to identify the specific viruses present. By analyzing the diversity of these viruses, the research aims to provide insights into how these animals can be used in future coronavirus studies and vaccine development.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of coronavirus immunity and improve strategies for managing COVID-19 and other related diseases.
How similar studies have gone: Other research has shown success in understanding coronavirus dynamics in animal models, making this approach both relevant and promising.
Where this research is happening
-
Tulane University of Louisiana
New Orleans, United States Active
Researchers
- Principal investigator: Maness, Nicholas James — Tulane University of Louisiana
- Study coordinator: Maness, Nicholas James
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.