Understanding how seasonal changes affect aggression in humans
A Seasonal Switch: Alternative Neuroendocrine Mechanisms Regulating Aggression
This study is looking at how the hormone melatonin affects aggressive behavior and how it interacts with other hormones, hoping to find new ways to help people with conditions like ADHD, autism, and mood disorders.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Trustees of Indiana University NIH-funded |
| Lab location | 1 site (Bloomington, United States) |
| Project ID | NIH-11108521 on NIH RePORTER |
What this research studies
This research investigates the biological mechanisms that regulate aggressive behavior, particularly focusing on how the hormone melatonin influences aggression through adrenal hormones. By examining the interplay between environmental factors and neuroendocrine responses, the study aims to uncover the underlying causes of pathological aggression associated with various psychiatric disorders. Patients may benefit from insights gained into how these mechanisms operate, potentially leading to new treatment strategies for conditions like ADHD, autism, and mood disorders.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with ADHD, autism spectrum disorders, or other mood and anxiety disorders characterized by aggressive behavior.
Not a fit: Patients who do not exhibit aggressive behavior or do not have related psychiatric conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for individuals experiencing pathological aggression linked to psychiatric disorders.
How similar studies have performed: Previous research has shown promising results in understanding the neuroendocrine mechanisms of aggression, suggesting that this approach could yield valuable insights.
Where this research is happening
Bloomington, United States
- Trustees of Indiana University — Bloomington, United States (Active)
Researchers
- Principal investigator: Demas, Gregory E — Trustees of Indiana University
- Study coordinator: Demas, Gregory E
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.