NIH-funded research R21 grant

Understanding how school environments affect respiratory viruses in children

Official title: Molecular epidemiology of respiratory virus exposure in elementary schools

Funded at Massachusetts General Hospital · NIH-10783808 · Data updated 2026-11-12

This study is looking at how things in schools might affect kids' chances of catching respiratory viruses, like those that can trigger asthma, and it will test if using special air cleaners can help keep the air healthier for students.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionMassachusetts General Hospital
NIH-funded
Lab location1 site (Boston, United States)
Project startFebruary 10, 2023
Project endJanuary 31, 2026
Funding year2024
Award (this year)$212,882
NIH project number5R21AI175965-02
Project IDNIH-10783808 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are children aged 0-11 years who attend elementary schools and may be experiencing asthma or respiratory issues.

Less likely to help

Patients who are older than 11 years or do not have respiratory conditions may not benefit from this research.

What this research studies

This research investigates how the school environment contributes to children's exposure to respiratory viruses, particularly focusing on factors that can be modified to improve health outcomes. The study aims to identify specific elements within elementary schools that lead to increased respiratory virus exposure and to evaluate the effectiveness of interventions, such as portable HEPA air cleaners, in reducing this exposure. By analyzing the respiratory virome in schools compared to homes, the research seeks to establish a link between virus exposure and asthma symptoms in children. The ultimate goal is to create healthier indoor environments for students.

Why it matters

Potential benefit: If successful, this research could lead to improved asthma management and reduced respiratory illnesses among children in school settings.

How similar studies have gone: Previous studies have shown success in using environmental interventions to reduce respiratory illnesses in children, indicating that this approach has potential.

Where this research is happening

  • Massachusetts General Hospital
    Boston, United States
    Active

Researchers

  • Principal investigator: Lai, Peggy Sue — Massachusetts General Hospital
  • Study coordinator: Lai, Peggy Sue

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.