Understanding how satellite cells affect muscle growth in older adults
The role of satellite cells in skeletal muscle hypertrophy with aging
This study is looking at how special cells in your muscles can help you grow stronger as you get older, especially when you exercise, and it hopes to find ways to keep your muscles healthy and prevent muscle loss as you age.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Kentucky NIH-funded |
| Lab location | 1 site (Lexington, United States) |
| Project ID | NIH-11088735 on NIH RePORTER |
What this research studies
This research investigates the role of satellite cells in promoting muscle growth as people age. It aims to uncover the cellular and molecular mechanisms that contribute to the loss of muscle mass in older adults, which can lead to serious health issues. By examining how satellite cells respond to exercise and other stimuli, the study seeks to identify potential therapeutic strategies to enhance muscle regeneration and growth. The research involves mechanistic analyses to understand how these cells can support muscle health in aging populations.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults aged 65 and older who are experiencing muscle loss or related health issues.
Not a fit: Patients under the age of 65 or those without significant muscle loss may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that help older adults maintain or regain muscle mass, improving their overall health and quality of life.
How similar studies have performed: Previous research has shown promising results in understanding the role of satellite cells in muscle growth, indicating that this approach has potential for success.
Where this research is happening
Lexington, United States
- University of Kentucky — Lexington, United States (Active)
Researchers
- Principal investigator: Mccarthy, John Joseph — University of Kentucky
- Study coordinator: Mccarthy, John Joseph
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.