Understanding how SARS-CoV-2 assembles and spreads
Elucidation of Assembly and Budding Mechanisms of SARS-CoV-2
This study is looking at how the COVID-19 virus puts itself together and spreads in our cells, which could help find new ways to treat the virus and improve our understanding of how it works.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Purdue University NIH-funded |
| Lab location | 1 site (West Lafayette, United States) |
| Project ID | NIH-10884326 on NIH RePORTER |
What this research studies
This research investigates the mechanisms by which the SARS-CoV-2 virus assembles and buds from host cells, which is crucial for understanding its replication and spread. The team will conduct in vitro and cellular studies, combined with computational analysis, to explore how the virus interacts with host cell lipids to form its protective envelope. By elucidating these processes, the research aims to identify potential new drug targets that could lead to effective treatments for COVID-19. The findings could significantly enhance our understanding of viral behavior and inform therapeutic strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals affected by COVID-19 or those at high risk of infection.
Not a fit: Patients who are not infected with SARS-CoV-2 or those who have already recovered from COVID-19 may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to the development of new therapeutics for COVID-19, improving patient outcomes.
How similar studies have performed: Previous research on coronaviruses has shown success in understanding their mechanisms, suggesting that this approach could yield valuable insights.
Where this research is happening
West Lafayette, United States
- Purdue University — West Lafayette, United States (Active)
Researchers
- Principal investigator: Stahelin, Robert Virgil — Purdue University
- Study coordinator: Stahelin, Robert Virgil
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.