Understanding how Salmonella bacteria become resistant to antibiotics
Emerging novel mechanisms of antibiotic resistance in the prevalent foodborne pathogen, Salmonella
This study is looking at how Salmonella, a germ that can make people sick from food, becomes resistant to antibiotics, so we can find new ways to help treat and prevent these infections that affect many people each year.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project ID | NIH-10681219 on NIH RePORTER |
What this research studies
This research investigates the mechanisms by which Salmonella, a common foodborne pathogen, develops resistance to antibiotics. By studying the genetic factors that contribute to antibiotic resistance, the research aims to identify new genes critical for resistance to key antibiotics like ceftriaxone and ciprofloxacin. The team will utilize advanced microbial genomics and computational methods to analyze a large collection of pathogen isolates and their characteristics. This work is essential for developing better strategies to prevent and treat Salmonella infections, which affect millions of people each year.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have experienced Salmonella infections, particularly those with antibiotic-resistant strains.
Not a fit: Patients with non-infectious conditions or those not affected by Salmonella infections may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments and prevention strategies for antibiotic-resistant Salmonella infections.
How similar studies have performed: Previous research has shown success in understanding antibiotic resistance mechanisms in other bacteria, suggesting that this approach could yield valuable insights.
Where this research is happening
Stanford, United States
- Stanford University — Stanford, United States (Active)
Researchers
- Principal investigator: Bhatt, Ami Siddharth — Stanford University
- Study coordinator: Bhatt, Ami Siddharth
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.