Understanding how RNA regulation affects Chronic Obstructive Pulmonary Disease
Official title: Post-transcriptional regulatory networks in Chronic Obstructive Pulmonary Disease
Funded at University of Virginia · NIH-11022330 · Data updated 2026-11-12
This study is looking at how certain proteins that interact with RNA might affect the way your body handles Chronic Obstructive Pulmonary Disease (COPD), with the hope of finding new ways to understand and treat the condition.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Virginia NIH-funded |
| Lab location | 1 site (Charlottesville, United States) |
| Project start | May 1, 2025 |
| Project end | February 28, 2030 |
| Funding year | 2025 |
| Award (this year) | $708,063 |
| NIH project number | 1R01HL176576-01 |
| Project ID | NIH-11022330 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with Chronic Obstructive Pulmonary Disease.
✕Less likely to help
Patients with other respiratory conditions that are not COPD may not receive benefit from this research.
What this research studies
This research investigates the role of post-transcriptional regulation of RNA in Chronic Obstructive Pulmonary Disease (COPD). By examining how RNA binding proteins (RBPs) interact with RNA molecules, the study aims to uncover the molecular mechanisms that contribute to COPD. The researchers will analyze changes in RNA levels and their impact on protein function, using advanced techniques to create regulatory networks specific to COPD. This approach could lead to a better understanding of the disease and potential new therapeutic targets.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that improve the management of COPD and enhance patient outcomes.
How similar studies have gone: Previous research has shown promising results in understanding RNA regulation in other diseases, suggesting that this approach could yield valuable insights for COPD as well.
Where this research is happening
-
University of Virginia
Charlottesville, United States Active
Researchers
- Principal investigator: Platig, John — University of Virginia
- Study coordinator: Platig, John
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.