Understanding how RNA-protein complexes are passed to future generations
Biochemistry in situ to determine inheritance of RNA-protein complexes
This study looks at how tiny RNA-protein teams are passed down from parents to their offspring in a small worm called C. elegans, helping us learn more about how these teams support growth and immunity, which could change how we think about genetics.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Indiana University Indianapolis NIH-funded |
| Lab location | 1 site (Indianapolis, United States) |
| Project ID | NIH-10918054 on NIH RePORTER |
What this research studies
This research investigates the inheritance of RNA-protein complexes, which are crucial for the development and immunity of organisms. By studying the model organism C. elegans, the researchers aim to identify which RNA binding proteins are inherited and how these complexes are organized at a molecular level. The project will utilize advanced biochemistry techniques to track these proteins across cell generations and from parents to offspring, providing insights into their roles in cellular development. This work could reshape our understanding of genetic inheritance beyond just DNA.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research would include individuals interested in genetic inheritance and its effects on development, particularly those with conditions related to RNA-protein interactions.
Not a fit: Patients with conditions unrelated to genetic inheritance or RNA-protein interactions may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new insights into genetic inheritance and its implications for development and disease.
How similar studies have performed: While the study of RNA-protein complexes is a growing field, this specific approach to understanding their inheritance is relatively novel and has not been extensively tested.
Where this research is happening
Indianapolis, United States
- Indiana University Indianapolis — Indianapolis, United States (Active)
Researchers
- Principal investigator: Aoki, Scott T — Indiana University Indianapolis
- Study coordinator: Aoki, Scott T
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.